Meloxicam SR is available from ZooPharm by prescription in vials containing 5 ml volume of the formulation, in a sustained release biodegradable matrix (at a concentration of 2 mg/ml).
Contraindications and Precautions:
Although meloxicam is COX-2 selective, at higher doses its specificity is diminished and more GI distress may be seen.1,5GI distress is usually transient and subsides with a dose decrease or termination of therapy.6 The use of meloxicam is contraindicated during pregnancy and lactation.6,7Meloxicam should not be used in dogs younger than 6 weeks of age.6Use is also contraindicated in animals suffering from GI disorders or impaired hepatic, cardiac, or renal function.1,5,6
Extreme caution should be used in animals that are dehydrated, hypovolemic, or hypotensive because there is an increased risk of renal toxicity.5,6
CONTRAINDICATIONS: Meloxicam SR is contraindicated for use in cats.
Meloxicam is highly protein bound; therefore, it can be displacedby other highly protein-bound drugs such as warfarin and phenylbutazone, resulting in toxicity.5,,6 Because meloxicam may inhibit platelet aggregation and also cause GI ulceration, it should not be used with other drugs that alter hemostasis or cause GI ulceration, including heparin, warfarin, aspirin, flunixin, phenylbutazone, and corticosteroids.5Meloxicam may antagonize the antihypertensive effects of angiotensin-converting enzyme inhibitors.5